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Spring 2001: BIOL 536: Computational Biology

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overview

overview

location 10 Leidy Laboratories
time MW 3:30-5
syllabus BIOL 536 Syllabus + Schedule
blackboard BIOL 536 Blackboard site

This course is designed to provide a rigorous hands-on introduction to the biological side of computational biology. Classroom lectures focus on the algorithms used for solving applied problems such as the assembly of contigs from molecular sequence data, similarity searching, gene finding and annotation, multiple sequence alignments and phylogenetics. Lectures are also supplemented with demonstrations and computer laboratory assignments.

BIOL 536 is designed for computer science and engineering students who require a better grasp of molecular biology and bioinformatics and for biology students interested in becoming skilled users of molecular genetic analysis applications.

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instructors

professors

Warren Ewens
221 Leidy Laboratories
email: wewens@sas.upenn.edu
+1 215 898.7109
Jessica Kissinger
212 Goddard Laboratories
email: jkissing@sas.upenn.edu
+1 215 898.1205
office hours: Fridays 1-2 PM
Elisabetta Manduchi
email: manduchi@pcbi.upenn.edu

teaching assistants

Li Li
100 Goddard Laboratories
email: lili4@sas.upenn.edu
office hours: TBA

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course information

course information

computer access

    Alex Reynolds is the system administrator for this lab and can be reached at bio-computing@sas.upenn.edu. However, please contact the TA, Li Li for ALL computer/software problems except account set-up and the physical functioning of the machines/printer.

textbook

    The following reading is available at the University of Pennsylvania bookstore:

    • Genomes, T.A. Brown
    • Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, edited by Baxevanis and Ouellette.

    In the case of students with a poor biology background, and those registered for CIS 535, the book Genomes is required. Please download and read the BIOL 536 syllabus for a list of additional recommended background reading.

grading and exams

    Grading is as follows:

    • Mid-term Exam = 25%
    • Homework/Paper Summaries = 50% (drop lowest)
    • Final project = 25%

    The "Practice" assignments are designed to fill in any missing background knowledge in Molecular Biology, Taxonomy and Basic Perl programming . The goal of these assignments is for you to learn as much as possible, by any means necessary. You may work in groups, collaborate, share, teach each other etc. These exercises MUST be turned in to pass the course, but they will not be graded. They are for your benefit and are crucial for your growth as a bioinformaticist and for completing the remaining "Homework" assignments.

    Homework assignments and paper summaries are not "group" activities, however. While I encourage you, when stuck, to discuss "issues", "concepts" and "themes" with whomever, especially when it concerns the location or usage of a particular piece of software, this discussion is not to include particulars relevant to the "intellectual" portion of the exercise. All work is to be done independently.

lecture schedule

    Please refer to the BIOL 536 PDF syllabus for more information on this course.

academic integrity

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downloads

downloads

 schedules
 assignments + handouts
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 exams
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course updates

course updates

01/10/2001
Page added

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Courses
Department of Biology
School of Arts and Sciences
University of Pennsylvania

last updated September 28, 2001