BIOL422 - GENOMICS OF DISEASE&EVOL

In this course we will discuss the identification and characterization of genetic diversity in the human genome, the genetic basis of normal variable traits, and the genetic basis of human disease. The study of the human genome increasingly impacts almost every aspect of our society, from medicine to law enforcement to how we view ourselves. The focus of this course will be to apply concepts and methods of genetics and genomic analysis (gene mapping, genome sequencing, epigenetics, gene expression) to better understand the genetic basis of both normal variable traits as well as disease. We will discuss how to distinguish the evolutionary and demographic forces (i.e. mutation, migration, selection, population size) that influence genotypic and phenotypic variation within and among human populations. We will discuss how genomics and population genetics methodologies are being applied to study modern human origins, analysis of ancient DNA, ancestry, and population history. We will also discuss the implications of these studies for personalized medicine.
Section 401 - LEC
TR 1200PM-0130PM
TISHKOFF, SARAH
LEIDY LAB 109