BIOL483 - Epigenetics

Activity
LEC
Section number integer
401
Title (text only)
Epigenetics
Term
2019C
Subject area
BIOL
Section number only
401
Section ID
BIOL483401
Course number integer
483
Meeting times
TR 01:30 PM-03:00 PM
Meeting location
LEVN 111
Level
undergraduate
Instructors
Doris Wagner
Description
This course investigates epigenetic phenomena: heritable alternate states of gene activity that do not result from an alteration in nucleotide composition (mutations). Epigenetic mechanisms regulate genome accessibility and cell differentiation. They play a key role in normal development and in oncogenesis. For example both mammalian X-chromosome inactivation and nuclear transfer (cloning) are subject to epigenetic regulation. Amongst the epigenetic mechanisms we will discuss in this course are chromatin organization, histone modification, DNA methylation and non-coding RNAs. The course is geared toward advanced undergraduate and beginning graduate students and is a combination of lectures, student presentations and research presentations by guest speakers. Students will work with the current scientific literature.
Course number only
483
Cross listings
CAMB483401
Use local description
No