Biology is fundamental to our changing world. The 21st century challenge for our students, our scholars, and the greater society is to understand our place in this changing world and to create fundamental knowledge for informed policies, economies, and social structure.
Giant ‘polytene’ chromosomes (white) from a fruit fly with a fluorescent probe (red) that hybridizes to a telomere-restricted DNA repeat.
Structural model of a bacterial respiratory complex III: remember that when you respire, your complex III perspires to produce your body's energy.
Many genes that organisms use to regulate their mutualists are also used to defend against parasites and pathogens. The shared genetic control of beneficial and harmful symbioses raises the intriguing possibility that susceptibility to infection is a pleiotropic cost of mutualism. Our goal is to understand how a genetic tradeoff between attracting mutualists and repelling parasites has shaped the genomic architecture of traits mediating species interactions, and how ongoing conflict influences adaptation.
Malaria parasites (and their kin) can be viewed as minimal eukaryotes, harboring a nucleus (yellow), a secretory pathway the Golgi (purple) and specialized ‘rhotpry’ organelle (black), and two endosymbiotic organelles, the mitochondrion (red) and apicoplast (green).
Drosophila are small flies, typically pale yellow to reddish brown to black, with red eyes. Many species, including the noted Hawaiian picture-wings, have distinct black patterns on the wings. The plumose (feathery) arista, bristling of the head and thorax, and wing venation are characters used to diagnose the family.