BIOL483 - Epigenetics

Status
O
Activity
LEC
Section number integer
401
Title (text only)
Epigenetics
Term
2020C
Syllabus URL
Subject area
BIOL
Section number only
401
Section ID
BIOL483401
Course number integer
483
Registration notes
Crse Online: Sync & Async Components
Meeting times
TR 01:30 PM-03:00 PM
Level
undergraduate
Instructors
Doris Wagner
Description
This course investigates epigenetic phenomena: heritable alternate states of gene activity that do not result from an alteration in nucleotide composition (mutations). Epigenetic mechanisms regulate genome accessibility and cell differentiation. They play a key role in normal development and in oncogenesis. For example both mammalian X-chromosome inactivation and nuclear transfer (cloning) are subject to epigenetic regulation. Amongst the epigenetic mechanisms we will discuss in this course are chromatin organization, histone modification, DNA methylation and non-coding RNAs. The course is geared toward advanced undergraduate and beginning graduate students and is a combination of lectures, student presentations and research presentations by guest speakers. Students will work with the current scientific literature.
Course number only
483
Cross listings
CAMB483401
Use local description
No

A message from the Department of Biology

“The horrific killings of George Floyd, Breonna Taylor, Ahmaud Arbery, and so many others have shocked and saddened us all.  These are grim manifestations of ongoing racism, repression, and inflammation of hatred in our society.”—Amy Gutmann
 
The Department of Biology at the University of Pennsylvania affirms support for the life and value of all Black community members and acknowledges the pain that many are experiencing. We are committed to doing our part and taking concrete actions to form an inclusive, truthful, and compassionate academic community.

 

BIOL101 - Introduction To Biology A

Status
C
Activity
LAB
Section number integer
913
Title (text only)
Introduction To Biology A
Term session
1
Term
2020B
Subject area
BIOL
Section number only
913
Section ID
BIOL101913
Course number integer
101
Registration notes
Registration also required for Lecture (see below)
Meeting times
TR 11:30 AM-01:00 PM
Level
undergraduate
Instructors
Staver Bezhani
Description
General principles of biology focusing on the basic chemistry of life, cell biology, molecular biology, and genetics in all types of living organisms. Particular emphasis will be given to links between the fundamental processes covered and current challenges of humankind in the areas of energy, food, and health. (3 hrs. lec., 3 hrs. lab, 1.5 c.u.) Biology majors and pre-medical students should take either BIOL 101 or 121. BIOL 101 is the companion course to BIOL 102 and should be taken before BIOL 102.
Course number only
101
Use local description
No

Mark Goulian recipient of the 2020 Ira H. Abrams Memorial Award for Distinguished Teaching

This year’s recipients of the School’s highest teaching honor are Paul Goldin, Professor of East Asian Languages and Civilizations, and Mark Goulian, Charles and William L. Day Distinguished Professor in the Natural Sciences in the Department of Biology. Created in 1983, the Ira H. Abrams Award recognizes teaching that is intellectually challenging and exceptionally coherent and honors faculty who embody high standards of integrity and fairness, have a strong commitment to learning, and are open to new ideas.

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BIOL005 - The Genomic Revolution

Status
C
Activity
SEM
Section number integer
301
Title (text only)
The Genomic Revolution
Term
2020C
Syllabus URL
Subject area
BIOL
Section number only
301
Section ID
BIOL005301
Course number integer
5
Registration notes
Course is available to Freshmen.
Crse Online: Sync & Async Components
Freshman Seminar
Meeting times
TR 03:00 PM-04:30 PM
Level
undergraduate
Instructors
Eric S Weinberg
Description
The goal of this course is to convey a basic understanding of human genome science and in so doing, to learn of its impact on treatment of human disease and discernment of aspects of human identity. Our current understanding of the structure and function of genes will allow a personalized treatment for many diseases, but just how such advances are applied will involve ethical as well as scientific considerations. We will discuss how the field of genetics has been changed dramatically by the ability to clone and sequence genes, and then to be further transformed by massive sequencing of whole genomes. A major part of the course will be devoted to how these advances have led to understanding and treatment of genetic disease and cancer. We will also discuss the tremendous potential (and dangers) of gene editing advances. Finally, we will explore how genomics has allowed an understanding of deep human history, as well as the ability to decipher one's more immediate ancestry. Readings will be from a number of books written for an informed general audience rather than from a textbook. The seminar should be of interest to those who would like to fulfill their Living World General Education requirement, and particularly also to those who eventually might be interested in taking courses in the Life Sciences but initially would like an introductory seminar-type approach within a focused area.
Course number only
005
Use local description
No

BIOL700 - Advanced Topics in Current Biology Research

Status
O
Activity
SEM
Section number integer
301
Title (text only)
Advanced Topics in Current Biology Research
Term
2020C
Subject area
BIOL
Section number only
301
Section ID
BIOL700301
Course number integer
700
Registration notes
Permission Needed From Department
For PhD Students Only
Crse Online: Sync & Async Components
Meeting times
R 02:00 PM-04:00 PM
Level
graduate
Instructors
David S. Roos
Description
Integrative seminar on current biological research for first-year PhD students.
Course number only
700
Use local description
No

BIOL536 - Fundamentals of Computational Biology and Biological Data Analysis

Status
C
Activity
LEC
Section number integer
401
Title (text only)
Fundamentals of Computational Biology and Biological Data Analysis
Term
2020C
Subject area
BIOL
Section number only
401
Section ID
BIOL536401
Course number integer
536
Registration notes
Undergraduates Need Permission
For PhD Students Only
Crse Online: Sync & Async Components
Meeting times
MW 02:00 PM-03:30 PM
Level
graduate
Instructors
Junhyong Kim
Description
Introductory computational biology course designed for both biology students and computer science, engineering students. The course will cover fundamentals of algorithms, statistics, and mathematics as applied to biological problems. In particular, emphasis will be given to biological problem modeling and understanding the algorithms and mathematical procedures at the "pencil and paper" level. That is, practical implementation of the algorithms is not taught but principles of the algorithms are covered using small sized examples. Topics to be covered are: genome annotation and string algorithms, pattern search and statistical learning, molecular evolution and phylogenetics, functional genomics and systems level analysis. Prerequisite: College level introductory biology required; undergraduate or graduate level statistics taken previously or concurrently required; molecular biology and/or genetics encouraged; programming experience encouraged
Course number only
536
Cross listings
CIS536401, GCB536401
Use local description
No

BIOL527 - Genetics For Computational Biology

Status
O
Activity
REC
Section number integer
403
Title (text only)
Genetics For Computational Biology
Term
2020C
Subject area
BIOL
Section number only
403
Section ID
BIOL527403
Course number integer
527
Registration notes
Permission Needed From Instructor
Crse Online: Sync & Async Components
Registration also required for Lecture (see below)
Meeting times
W 01:00 PM-02:00 PM
Level
graduate
Description
This course will survey the discipline of molecular genetics. Two broad areas will be considered: 1) Molecular biology: DNA replication, transcription, translation, and the regulation of gene expression in both prokaryotic and eukaryotic systems and genomics and 2) Genetics: basic Mendelian & molecular genetics.
Course number only
527
Cross listings
BIOL221403
Use local description
No