Status
C
Activity
LEC
Section number integer
401
Title (text only)
Epigenetics
Term
2018C
Subject area
BIOL
Section number only
401
Section ID
BIOL483401
Course number integer
483
Meeting times
TR 01:30 PM-03:00 PM
Meeting location
LEVN 111
Level
undergraduate
Instructors
Doris Wagner
Description
This course investigates epigenetic phenomena: heritable alternate states of gene activity that do not result from an alteration in nucleotide composition (mutations). Epigenetic mechanisms regulate genome accessibility and cell differentiation. They play a key role in normal development and in oncogenesis. For example both mammalian X-chromosome inactivation and nuclear transfer (cloning) are subject to epigenetic regulation. Amongst the epigenetic mechanisms we will discuss in this course are chromatin organization, histone modification, DNA methylation and non-coding RNAs. The course is geared toward advanced undergraduate and beginning graduate students and is a combination of lectures, student presentations and research presentations by guest speakers. Students will work with the current scientific literature.
Course number only
483
Cross listings
CAMB483401
Use local description
No